Moderate-HighGBS: 84 (High Risk)nutrition

PCOS Reversal Protocol

Developer: Fiona McCulloch, functional medicine approaches

3-6 months to see hormonal improvements, 6-12 months for sustained reversal

Protocol Overview

Comprehensive root-cause protocol addressing insulin resistance, inflammation, and hormonal imbalances in PCOS. Goes beyond metformin to address diet, supplements, and lifestyle factors.

Conditions Treated

PCOS (polycystic ovary syndrome)

irregular periods

hirsutism

infertility

insulin resistance

Protocol Steps

Testing: Fasting insulin and glucose (calculate HOMA-IR), testosterone (total and free), DHEA-S, LH/FSH ratio, progesterone, thyroid, inflammatory markers (CRP), consider genetic testing (PCOS subtypes)

Diet - Low glycemic, anti-inflammatory: Eliminate sugar, refined carbs, reduce overall carbs (40% or less of calories), emphasize protein (25-30%), healthy fats, high fiber (35g+), no dairy initially (dairy raises insulin), organic to avoid endocrine disruptors

Inositol: Myo-inositol 2000mg + D-chiro-inositol 50mg twice daily (40:1 ratio studied for PCOS) - improves insulin sensitivity, egg quality, ovulation. Ovasitol is researched brand

Berberine or metformin: Berberine 500mg 3x/day with meals (natural metformin alternative, improves insulin sensitivity) OR metformin 500-1500mg if prescribed

NAC: 600mg 3x/day - improves insulin sensitivity, reduces testosterone, improves ovulation rate

Vitamin D: 4000-5000 IU daily (most PCOS patients deficient, improves insulin and fertility)

Omega-3: 2-3g EPA/DHA daily for anti-inflammatory effects

Saw palmetto: 160mg 2x/day for hirsutism (blocks DHT), or spironolactone 100-200mg if prescribed

Spearmint tea: 2 cups daily reduces testosterone, improves hirsutism

Chromium: 200-1000mcg for blood sugar control

Magnesium: 400mg daily (improves insulin sensitivity)

Cinnamon: 1-2g daily for blood sugar

Exercise: High-intensity interval training or strength training 3-4x/week (improves insulin sensitivity more than steady cardio), don't overexercise (raises cortisol)

Stress management: Chronic stress worsens PCOS - meditation, adaptogenic herbs (rhodiola, ashwagandha), adequate sleep

Weight loss if overweight: Even 5-10% weight loss restores ovulation in many cases

Key Resources

8 Steps to Reverse Your PCOS by Fiona McCulloch, PCOS Nutrition Center, research on inositol for PCOS, functional medicine protocols

Contraindications & Risks

Berberine interacts with some medications, coordinate with provider, pregnancy (some supplements need adjustment)

Important Notes

PCOS is most common hormonal disorder in women (8-13%). Root cause is insulin resistance in ~70% of cases. Inositol is game-changer - RCTs show improved ovulation, pregnancy rates, reduced testosterone. Myo-inositol:D-chiro ratio of 40:1 is crucial (Ovasitol). Berberine as effective as metformin in studies. NAC improves multiple PCOS parameters. Diet is foundation - low glycemic, avoid dairy (raises IGF-1 and insulin). Exercise type matters - HIIT/strength better than long cardio. Weight loss not required for all (lean PCOS exists) but helps if overweight. Spearmint tea simple addition. Birth control often prescribed but doesn't address root cause. Natural approach can reverse PCOS in many cases - restore ovulation, reduce symptoms, improve fertility.

Also Effective For

PCOS (Polycystic Ovary Syndrome)Infertility Type 2 Diabetes Reversal

Key Supplements & Herbs in This Protocol

Supplements

Berberine

Herbs

Ashwagandha

Withania somnifera

Rhodiola

Rhodiola rosea

Saw Palmetto

Serenoa repens

Critical Safety Warning

This protocol is documented for educational purposes only. The Gabriel Bullshit Score (GBS) of 84 reflects significant institutional response and controversy. Some alternative health protocols have resulted in serious harm or death.

Always consult with qualified healthcare professionals before beginning any treatment. Do not delay or forego proven medical care.

Quick Overview

Evidence LevelModerate-High

GBS Score84 / 100

Categorynutrition

DeveloperFiona McCulloch, functional medicine approaches

Duration3-6 months to see hormonal improvements, 6-12 months for sustained reversal

About GBS Score

The Gabriel Bullshit Score reflects the magnitude of institutional response, controversy, and documented concerns. Higher scores indicate greater institutional pushback, not necessarily inefficacy. This is a research tool, not medical advice.