Low-ModerateGBS: 71 (Moderate-High Risk)autoimmune

Long COVID Recovery Protocol

Developer: Various long COVID clinics, integrative medicine

3-18 months recovery variable, some chronic

Protocol Overview

Comprehensive protocol addressing persistent inflammation, mast cell activation, mitochondrial dysfunction, and autonomic dysfunction after COVID-19 infection. Emerging evidence-based approach.

Conditions Treated

Long COVID

post-acute sequelae of COVID-19

PASC

Protocol Steps

Symptom categorization: Fatigue/PEM (post-exertional malaise), brain fog, dysautonomia (POTS-like), breathing issues, MCAS symptoms - identify dominant pattern

Rule out: Active infection, reactivated viruses (EBV, HHV-6 - check IgG/IgM), thyroid dysfunction, anemia, vitamin deficiencies

Pacing/energy envelope: Strict pacing to avoid PEM crashes - track HRV, stay within 60-70% of capacity, rest before symptoms appear (like ME/CFS management)

Anti-inflammatory diet: Eliminate processed foods, sugar, gluten, dairy trial, emphasize colorful vegetables, omega-3 fish, berries, turmeric

Low-histamine diet: If MCAS symptoms (flushing, hives, GI issues) - avoid fermented foods, aged cheese, alcohol, histamine-rich foods

Omega-3: 3-4g EPA/DHA (anti-inflammatory, many long COVID patients benefit)

Vitamin D: Optimize 60-80 ng/ml (immune modulation, many long COVID patients deficient)

NAC: 600-1200mg 2x/day (glutathione support, antioxidant, may reduce inflammation)

Quercetin: 500mg 2x/day (mast cell stabilizer, antiviral properties, zinc ionophore)

Vitamin C: 1-3g daily (antioxidant, immune support)

B-complex: Methylated B-vitamins (mitochondrial support, many long COVID patients have methylation issues)

Coenzyme Q10: 200-400mg ubiquinol (mitochondrial support for fatigue)

D-ribose: 5g 2-3x/day (cellular energy production, helps fatigue)

Magnesium: 400-800mg (mitochondrial function, muscle relaxation)

LDN (Low-Dose Naltrexone): 1.5-4.5mg at night (immune modulation, reduces neuroinflammation - many long COVID patients report benefit)

Antihistamines: H1 blocker (cetirizine/loratadine) + H2 blocker (famotidine) if MCAS symptoms

Ivermectin: Controversial but some long COVID clinics use 12-18mg weekly for persistent viral fragments (no RCT data)

Metformin: 500-1000mg daily (emerging data on reduced long COVID risk if taken during acute infection, mitochondrial benefits)

Maraviroc or CCR5 antagonists: Experimental - some long COVID specialists using for inflammation (prescription)

Breathing exercises: Vagal nerve stimulation, diaphragmatic breathing, Wim Hof method (may help dysautonomia and breathing issues)

Dysautonomia support: Increase salt and fluid intake, compression stockings, beta-blockers if POTS-like symptoms

Stellate ganglion block: For severe dysautonomia - interventional procedure showing promise

Hyperbaric oxygen: Emerging data - some long COVID clinics using HBOT protocols

Treat reactivated viruses: If EBV/HHV-6 IgM positive, consider antivirals (valacyclovir, famciclovir)

PT/OT: Graded exercise only after PEM resolved (too early worsens condition - unlike other conditions where early exercise helps)

Key Resources

Long COVID clinic protocols, IncellDx (Bruce Patterson's research), Body Politic support group, Survivor Corps

Contraindications & Risks

LDN generally safe, ivermectin controversial, pacing is crucial (premature exercise worsens), coordinate with long COVID-literate provider

Important Notes

Long COVID (PASC) affects 10-30% of COVID-19 survivors - millions worldwide. Symptoms: Debilitating fatigue with PEM, brain fog, dysautonomia (POTS-like), breathing issues, MCAS symptoms, exercise intolerance. Mechanisms unclear but inflammation, autoimmunity, viral persistence, mast cell activation, mitochondrial dysfunction, autonomic dysfunction all implicated. Pattern recognition: Looks like ME/CFS + MCAS + dysautonomia. Pacing is crucial - post-exertional malaise worsens with activity (opposite of deconditioning - rest is needed). Many providers mistakenly push exercise too early, causing crashes. HRV monitoring helps guide activity. MCAS symptoms common - low-histamine diet and antihistamines (H1+H2 blockers) help many. LDN emerging as helpful (immune modulation). NAC, quercetin, vitamin D basics. Mitochondrial support (CoQ10, D-ribose, B-vitamins) for energy. Some clinics using ivermectin for persistent viral fragments (controversial, no RCT). Reactivated viruses (EBV, HHV-6) in subset - treat with antivirals. Metformin emerging as potential preventive/treatment. Hyperbaric oxygen showing promise in case series. Dysautonomia managed like POTS (salt, fluids, compression, sometimes beta-blockers). Stellate ganglion block for severe autonomic dysfunction. Recovery highly variable - some months, some years, some chronic. Comprehensive approach addressing multiple pathways. Long COVID clinics emerging (Mount Sinai, Stanford, etc.). Validate patient suffering - many dismissed by mainstream medicine.

Also Effective For

Long COVID

Key Supplements & Herbs in This Protocol

Supplements

Quercetin

Herbs

Turmeric

Curcuma longa

Critical Safety Warning

This protocol is documented for educational purposes only. The Gabriel Bullshit Score (GBS) of 71 reflects significant institutional response and controversy. Some alternative health protocols have resulted in serious harm or death.

Always consult with qualified healthcare professionals before beginning any treatment. Do not delay or forego proven medical care.

Quick Overview

Evidence LevelLow-Moderate

GBS Score71 / 100

Categoryautoimmune

DeveloperVarious long COVID clinics, integrative medicine

Duration3-18 months recovery variable, some chronic

About GBS Score

The Gabriel Bullshit Score reflects the magnitude of institutional response, controversy, and documented concerns. Higher scores indicate greater institutional pushback, not necessarily inefficacy. This is a research tool, not medical advice.