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The ketogenic diet is a high-fat, adequate-protein, very-low-carbohydrate eating pattern that shifts the body's primary fuel source from glucose to ketones. When carbohydrate intake drops below about 50 grams per day, the liver begins converting fat into ketone bodies, which can cross the blood-brain barrier and provide an alternative, highly efficient fuel for the brain and body. This metabolic state, called ketosis, has profound therapeutic effects beyond simple weight loss, it reduces inflammation, stabilizes blood sugar, enhances mental clarity, and has been shown to benefit numerous medical conditions.
Therapeutic ketogenic diets are more structured and precise than popular "keto" weight-loss diets. Medical professionals carefully calculate macronutrient ratios (typically 70-80% fat, 15-20% protein, 5-10% carbohydrates), monitor ketone levels, and adjust based on therapeutic goals. The classic ketogenic diet was developed in the 1920s as a treatment for epilepsy and remains highly effective for seizure control. Modern applications include neurodegenerative diseases (Alzheimer's, Parkinson's), cancer metabolism therapy, diabetes and metabolic syndrome, PCOS, and mental health conditions.
Transitioning to ketosis requires guidance and monitoring, especially for medical applications. Initial "keto flu" symptoms (fatigue, headaches, irritability) are common as the body adapts. Working with a knowledgeable practitioner ensures proper implementation, adequate micronutrient intake, and monitoring of relevant biomarkers. For appropriate candidates, therapeutic ketosis can be truly transformative, providing not just symptom relief but fundamental metabolic optimization that supports long-term health and disease prevention.
The ketogenic diet has extensive research support, particularly for epilepsy where it's an established medical treatment. Growing evidence supports benefits for Alzheimer's, Parkinson's, cancer, and metabolic health. When properly implemented under medical supervision, it's safe for most people. Contraindications include certain metabolic disorders and some medications. Working with knowledgeable practitioners ensures safe implementation and optimal therapeutic benefit.
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