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Systemic enzyme therapy uses oral supplementation of proteolytic enzymes (protein-digesting enzymes) taken between meals to reduce inflammation, break down scar tissue and fibrin, improve circulation, and support immune function. Unlike digestive enzymes taken with food, systemic enzymes are absorbed into the bloodstream where they exert therapeutic effects throughout the body.
Key enzymes used in systemic therapy include bromelain (from pineapple), papain (from papaya), serrapeptase (from silkworms), nattokinase (from fermented soybeans), and animal-derived pancreatic enzymes. These enzymes break down inflammatory proteins, reduce swelling, improve blood flow, and help clear cellular debris.
Systemic enzyme therapy is used for sports injuries, post-surgical recovery, chronic inflammation, arthritis, fibromyalgia, and cardiovascular health. It's particularly popular in European countries where enzyme therapy is mainstream medical practice. The approach offers a natural anti-inflammatory alternative to NSAIDs without the gastrointestinal side effects.
Systemic enzyme therapy has moderate research support, particularly in European medical literature. Studies show benefits for post-surgical swelling, sports injuries, and arthritis. Enzymes are generally safe when taken as directed. People on blood thinners should consult their physician as some enzymes have mild blood-thinning effects. Quality and potency of enzyme products vary significantly—pharmaceutical-grade formulations are preferred.
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