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Chelation therapy uses intravenous infusion of EDTA (ethylenediaminetetraacetic acid) or other chelating agents to bind heavy metals and remove them from the body through urine. Originally developed to treat lead poisoning, chelation has expanded to include treatment for mercury, cadmium, and other toxic metals, as well as controversial use for cardiovascular disease. EDTA is a synthetic amino acid that acts like a molecular claw, grabbing onto metal ions and forming stable complexes that are safely eliminated through the kidneys.
Heavy metal toxicity is an underrecognized contributor to chronic disease. Metals like lead, mercury, cadmium, and arsenic accumulate in tissues over decades of exposure from food, water, air pollution, dental amalgams, and occupational exposures. These metals interfere with enzymatic processes, generate oxidative stress, disrupt hormones, and damage cellular structures. Symptoms are often vague and nonspecific (fatigue, brain fog, mood issues) making diagnosis challenging. Chelation offers a way to remove these stored toxins and reduce their burden on the body.
Beyond heavy metal removal, some practitioners use chelation for cardiovascular disease, based on the theory that EDTA removes calcium from arterial plaques and reduces oxidative stress. This application remains controversial, though some research shows benefits. Chelation requires careful medical supervision including kidney function monitoring, mineral replacement, and screening for contraindications. For people with documented heavy metal toxicity or as part of comprehensive cardiovascular protocols, chelation offers targeted detoxification that other methods cannot achieve.
Chelation therapy is FDA-approved and well-established for heavy metal poisoning. Its use for cardiovascular disease is more controversial, though the TACT trial (NIH-funded) showed some benefits. When performed by experienced physicians with proper monitoring, chelation is safe. Risks include mineral depletion (addressed through supplementation) and rare kidney stress. Kidney function must be adequate. Overall, a legitimate therapy for appropriate indications under proper medical supervision.
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