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Off-label use of alcoholism drug (Antabuse) at high doses to kill Borrelia persisters. Emerging as most effective treatment for chronic Lyme. Requires careful monitoring.
Diagnosis: Chronic Lyme confirmed (clinical + labs), failed other antibiotics
Start low: 62.5mg daily for 1 week
Increase gradually: 125mg for 1 week, 250mg for 1 week, then 375-500mg daily
Target dose: 250-500mg daily (higher than alcoholism dose of 250mg)
Duration: 6-18 months typical, some need longer
Monitoring: Liver enzymes monthly (hepatotoxicity risk), psychiatric symptoms (can cause psychosis), peripheral neuropathy
No alcohol: Absolutely no alcohol (severe disulfiram-alcohol reaction)
Pulse dosing: Some use 4 days on, 3 days off to reduce side effects
Herxheimer reactions: Common and can be severe - detox support essential
Combination: Often combined with other antibiotics or herbs for coinfections
Game-changer in Lyme treatment according to many patients. Discovered by Stanford screen. Kills persister forms of Borrelia that other antibiotics miss. Can cause severe side effects (neuropathy, psychosis). Requires close monitoring. Many Lyme patients report sustained remission after years of suffering. Off-label use, not FDA-approved for Lyme. Most exciting Lyme treatment in years.
This protocol is documented for educational purposes only. The Gabriel Bullshit Score (GBS) of 74 reflects significant institutional response and controversy. Some alternative health protocols have resulted in serious harm or death.
Always consult with qualified healthcare professionals before beginning any treatment. Do not delay or forego proven medical care.
The Gabriel Bullshit Score reflects the magnitude of institutional response, controversy, and documented concerns. Higher scores indicate greater institutional pushback, not necessarily inefficacy. This is a research tool, not medical advice.