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Passiflora incarnata
Tradition of Use: Western, Native American
Increases GABA levels, modulates benzodiazepine receptors, mild MAO inhibition
Tea, tincture, capsule
250-500mg or 1-4ml tincture up to 4x daily
Flavonoids (chrysin, vitexin), harmala alkaloids
Potentiates sedatives, MAO inhibitors, anticoagulants
Pregnancy; surgery (discontinue 2 weeks prior)
Evidence Level:
Moderate - effective for anxiety
Clinical Notes:
Gentler than valerian; synergistic with other calming herbs
This information is for educational purposes. Always consult with a qualified healthcare provider before starting any herbal protocol or supplement regimen.
Hypericum perforatum
Inhibits serotonin, dopamine, norepinephrine reuptake; modulates GABA and glutamate receptors
Silybum marianum
Hepatoprotective via silymarin (antioxidant, anti-inflammatory, regenerates hepatocytes)
Zingiber officinale
Anti-inflammatory, antiemetic, warming circulatory stimulant, digestive, analgesic