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Tanacetum parthenium
Tradition of Use: Western, European traditional
Inhibits prostaglandin synthesis, serotonin release, platelet aggregation, anti-inflammatory
Capsule, tincture, fresh leaf
50-150mg dried leaf (0.2% parthenolide) daily or 1-2 fresh leaves
Parthenolide, sesquiterpene lactones, flavonoids
May interact with anticoagulants, NSAIDs; can cause rebound headaches if stopped abruptly
Pregnancy; breastfeeding; ragweed allergy; surgery; anticoagulant use
Evidence Level:
Good - effective for migraine prevention
Clinical Notes:
Preventive, not acute treatment; takes 4-6 weeks; fresh leaf can cause mouth ulcers; don't stop abruptly
Xiao Bai Ju
Prevents migraines by reducing inflammation in blood vessels
This information is for educational purposes. Always consult with a qualified healthcare provider before starting any herbal protocol or supplement regimen.
Hypericum perforatum
Inhibits serotonin, dopamine, norepinephrine reuptake; modulates GABA and glutamate receptors
Silybum marianum
Hepatoprotective via silymarin (antioxidant, anti-inflammatory, regenerates hepatocytes)
Zingiber officinale
Anti-inflammatory, antiemetic, warming circulatory stimulant, digestive, analgesic