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Gabriel distinguishes TRUE adrenal insufficiency (life-threatening, needs hormone replacement) from HPA axis dysfunction ("adrenal fatigue"—cortisol dysregulation, recoverable).
Gabriel distinguishes TRUE adrenal insufficiency (life-threatening, needs hormone replacement) from HPA axis dysfunction ("adrenal fatigue"—cortisol dysregulation, recoverable). TRUE insufficiency: primary (Addison's—autoimmune) or secondary/tertiary (pituitary/hypothalamus) or iatrogenic (steroid-induced)—these need medical management, hydrocortisone replacement. Protocol for insufficiency: 1) Appropriate hormone replacement (hydrocortisone or prednisone—MUST HAVE, life-saving), 2) Stress-dose steroids during illness/surgery (adrenal crisis prevention—educate patient), 3) Electrolyte management (salt, fludrocortisone if mineralocorticoid deficient), 4) Support with adaptogens CAREFULLY (can help but not replacement), 5) Medical alert bracelet, 6) Emergency injection kit (for adrenal crisis). HPA dysfunction: see separate adrenal fatigue protocol—recoverable. Don't confuse the two—true insufficiency is medical emergency.
Standard Treatment
Hormone replacement: Hydrocortisone 15-25mg/day divided doses OR Prednisone 5-7mg/day, Fludrocortisone 0.05-0.2mg/day (if primary), Treat underlying cause if secondary/tertiary (pituitary tumor—surgery, radiation), Stress-dose protocols (illness, surgery), Emergency treatment of adrenal crisis (IV hydrocortisone 100mg, IV fluids, electrolytes, ICU if severe), Education (sick-day rules, emergency plan)
The Problem
Conventional management for true insufficiency is NECESSARY and life-saving (hormone replacement is not optional—adrenal insufficiency is fatal without treatment), patients MUST take steroids, BUT: Conventional approach often: Doesn't optimize DHEA replacement (improves quality of life, energy, mood—especially women, but rarely offered), Doesn't support with nutrients (vitamin C, B5, magnesium—adrenal support), Doesn't educate adequately about sick-day rules (many patients don't know to increase dose during illness—risk of crisis), Doesn't provide psychological support (living with chronic condition, anxiety about crisis), Doesn't distinguish HPA dysfunction from true insufficiency (many patients with "adrenal fatigue" symptoms told they're fine because ACTH stim test normal—but HPA dysregulation is real, different condition, recoverable), Overdiagnosis of insufficiency (some clinicians diagnose based on symptoms alone without proper testing—dangerous to put someone on long-term steroids unnecessarily), Underdiagnosis (some dismissed as "just tired"—true insufficiency missed, rare but serious), Dosing sometimes suboptimal (circadian dosing better—most in morning, some midday, small amount afternoon, mimics natural rhythm—many just given once or twice daily), Fludrocortisone dose (often needs adjustment based on symptoms, BP, electrolytes—sometimes inadequate), NOTE: This is one condition where hormone replacement is truly needed and life-saving—functional medicine supportive but not sufficient alone for true insufficiency (different from "adrenal fatigue"/HPA dysfunction which is recoverable without steroids)
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What's Included
Available through Fullscript
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What's Included
Whole food supplements by Standard Process
What's Included
Standard Process + Matter peptides
High-salt diet (primary insufficiency—need 3-6g extra sodium/day, salt food liberally, salt tablets), Adequate calories (metabolism affected), Regular meals (prevent hypoglycemia—cortisol helps maintain blood sugar), Protein adequate (adrenal hormone synthesis), Vitamin C foods (adrenals concentrate vitamin C—citrus, bell peppers, broccoli, strawberries), Avoid fasting (risk of hypoglycemia, adrenal crisis), Hydration critical (especially during illness, heat, exercise), Avoid alcohol (stresses system, hypoglycemia risk), Small frequent meals if hypoglycemia prone, Balanced macronutrients, Electrolyte-rich foods (potassium, sodium balance—bananas, avocado, sweet potato, spinach, coconut water)
Medical alert bracelet or necklace (CRITICAL—emergency personnel need to know, adrenal crisis is life-threatening), Emergency injection kit (hydrocortisone 100mg IM—for crisis, teach family/friends how to inject), Stress-dose steroids during illness/surgery (double or triple maintenance dose—prevents crisis, work with endocrinologist on sick-day rules), Avoid overexertion (can precipitate crisis—but gentle exercise okay), Adequate sleep (7-9 hours), Stress management (emotional stress can trigger crisis—meditation, therapy, support groups), Avoid extreme heat (dehydration risk), Travel preparedness (extra medication, emergency kit, medical documentation), Regular endocrinology follow-up, Educate family/friends (recognize crisis symptoms—severe weakness, confusion, abdominal pain, vomiting, low BP—call 911), Never abruptly stop steroids (must taper slowly—sudden withdrawal causes crisis), Sick-day protocol (increase steroid dose with illness, vomiting—go to ER if can't keep meds down), Medical ID card with diagnosis, medications, emergency contact, Gradual stress exposure (body can't mount normal cortisol response—avoid sudden physical/emotional stressors), Join support groups (Addison's community helpful—share experiences, tips)
Mind, Body & Spirit
True healing requires addressing all dimensions of health. These evidence-based practices complement physical treatment protocols.
Daily meditation practice to reduce stress, lower inflammation, and support healing.
Developing healthy coping strategies to reduce cortisol and support immune function.
Conscious breathing techniques to regulate nervous system and reduce symptoms.
Time in nature to reduce stress, improve mood, and support physical healing.
Corticosteroids suppress adrenal function and cause multiple serious side effects
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